Here is the full list of all 22 Profane achievements.
Complete all achievements
Unlock the 'Doom' ending
Have a 5 Daily win streak
Win a game in Challenge Mode
Use every ability
Beat a Boss without taking damage
Beat Garodal
Unlock the 'Freedom' ending
Die 10 times
Beat Cindael
Beat Sentiel
Beat Nuraanag
Beat Ylaudit
Beat a Boss with no remaining time
Beat Duhm
Beat Mobus
Beat Drakhul
Pick 50 souls
Beat Khalepo
Beat a boss without actives and passives
Beat Tutoriaal
Complete the tutorial