Here is the full list of all 30 Potionomics achievements.
you reject a character romantically
Beat the game
Beat Robin
Stress Fail with Sylvia
Give Luna a bug
Max the relationship with 10 characters in one playthrough
Max the relationship with 7 characters in one playthrough
Max the relationship with 3 characters in one playthrough
Fully Upgrade Store
Complete Maven's Tower Adventure Area
Make all level 6 tier potions
Beat Anubia
Beat an opponent having a potion that triggered the failsafe
Max a relationship with a character
Make a level 6 tier potion
Expand 100 Ingredients in one playthrough
Craft 300 Potions
Beat Boss Finn
you date a character romantically
Expand 60 Ingredients in one playthrough
Beat Corsac
Collect a medium size amount of money (2500 in Wallet)
Craft 100 Potions
Have 0 money in the bank
Expand 30 Ingredients in one playthrough
Fully upgrade any Cauldron or Shelf
Collect a large size amount of money (10000 in Wallet)
Beat Roxanne
Collect a small amount of money (500 in Wallet)
Obtained by clearing the first narrative beat in the game