Here is the full list of all 30 Potionomics achievements.
Beat the game
Beat Robin
Make all level 6 tier potions
Complete Maven's Tower Adventure Area
Max the relationship with 10 characters in one playthrough
Beat Anubia
Max the relationship with 7 characters in one playthrough
Fully Upgrade Store
Max the relationship with 3 characters in one playthrough
Make a level 6 tier potion
Beat Boss Finn
Craft 300 Potions
Max a relationship with a character
Expand 100 Ingredients in one playthrough
Stress Fail with Sylvia
Have 0 money in the bank
you date a character romantically
you reject a character romantically
Beat Corsac
Beat an opponent having a potion that triggered the failsafe
Expand 60 Ingredients in one playthrough
Give Luna a bug
Craft 100 Potions
Expand 30 Ingredients in one playthrough
Collect a medium size amount of money (2500 in Wallet)
Collect a large size amount of money (10000 in Wallet)
Beat Roxanne
Fully upgrade any Cauldron or Shelf
Collect a small amount of money (500 in Wallet)
Obtained by clearing the first narrative beat in the game