Here is the full list of all 30 Potionomics achievements.
you reject a character romantically
Stress Fail with Sylvia
Beat the game
Beat Robin
Give Luna a bug
Max the relationship with 10 characters in one playthrough
Max the relationship with 7 characters in one playthrough
Make all level 6 tier potions
Fully Upgrade Store
Max the relationship with 3 characters in one playthrough
Complete Maven's Tower Adventure Area
Beat Anubia
Max a relationship with a character
Make a level 6 tier potion
Beat Boss Finn
you date a character romantically
Expand 100 Ingredients in one playthrough
Craft 300 Potions
Beat Corsac
Fully upgrade any Cauldron or Shelf
Have 0 money in the bank
Expand 60 Ingredients in one playthrough
Collect a medium size amount of money (2500 in Wallet)
Craft 100 Potions
Expand 30 Ingredients in one playthrough
Collect a large size amount of money (10000 in Wallet)
Beat Roxanne
Beat an opponent having a potion that triggered the failsafe
Collect a small amount of money (500 in Wallet)
Obtained by clearing the first narrative beat in the game