Here is the full list of all 61 Polygod achievements.
Complete Mazu's Docks without killing a yellow submarine.
Beat the harder Holy Champion of Gaia by going through the red portal in the Garden of Gaia.
Kill all the enemies in the Fire Quarry of Wrath.
Kill all the enemies in Mazu's Docks.
Combine Frozen Core with Flaming Core.
Defeat the first Holy Champion with the Laser Shots Blessing.
Kill all the enemies in the Garden of Gaia.
Trigger every Doom Shroom in the Garden of Gaia. You may not destroy a Doom Shroom by any other means.
Kill all other beings in the first Room of Rest.
Kill Bran by knocking him off a ledge.
Defeat the first Holy Champion without the use of Blessings.
Defeat the second Holy Champion without the use of Blessings.
Defeat the first Holy Champion with the Bubble Bullets Blessing.
Complete the game without killing any ground-based enemies.
Die 1000 times.
Finish the game without losing health once.
Kill all the enemies in Harenam Hall.
Acquire two Fall Boots Blessings.
Do not let a baby jellyfish hatch during the second Holy Champion fight.
Combine Bubble Bullets with Proximity Mines.
Beat the game.
Sacrifice 5 hit points to the faceless statue in the Fire Quarry of Wrath.
Beat the game as Faceless the Wrathful.
Sacrifice 10 souls to the faceless statue in the Garden of Gaia.
Beat the game as Faceless the Feeble.
Beat the game as Faceless the Shadow.
Beat the game as Faceless the God.
Sacrifice any two blessings to the faceless statue in Harenam Hall.
Beat the game as Faceless the Friendly.
Defeat the second Holy Champion in under 30 seconds.
Beat the game as Faceless the Fast.
Sacrifice Heavy Core to the faceless statue in Mazu's Docks.
Beat the games as Faceless the Heavy.
Beat mortal mode.
Kill yourself in a Room of Rest.
Beat the game with every Faceless One.
Beat the game as Faceless the Foolish.
Beat the game as Faceless the Fey.
Beat the game as Faceless the Soulless.
Beat the game as Faceless the Fallen.
Beat the game as Faceless the Fury.
Beat the game as Faceless the Frozen.
Beat the game as Faceless the Fitful.
Defeat the harder Holy Champion of Mazu by going through the red portal in Mazu's Docks.
Defeat the harder Holy Champion of Harenam by going through the red portal in Harenam Hall.
Defeat the harder Holy Champion of Raika by going through the red portal in Raika's Rainforest.
Defeat the harder Holy Champion of Chaos by going through the red portal in the Abyss of Chaos.
Sacrifice Soul Core to the faceless statue in Raika's Rainforest.
Sacrifice Heart of Death to the faceless statue in the Abyss of Chaos.
Kill all the enemies in Raika's Rainforest.
Kill all the enemies in the Abyss of Chaos.
Kill all the enemies in the Void of Truth.
Defeat the third Holy Champion without the use of Blessings.
Defeat the fourth Holy Champion without the use of Blessings.
Defeat the fifth Holy Champion without the use of Blessings.
Combine Indomitable Will with Inconquerable Will.
Combine Death and Taxes with Blood Tax.
Combine Compound X81, Compound X82, Adrenaline and Anesthetic.
Ark has given you a gift for sparing his people.
Defeat the harder Holy Champion of Wrath by going through the red portal in the Fire Quarry of Wrath.
Defeat the sixth Holy Champion without the use of Blessings.