Here is the full list of all 50 Pathologic 2 achievements. It takes around 0-1 hour to unlock all of the achievements on Windows.
Witness all dreams—including those you'd rather not
Disperse all Reflections
Jump from the Polyhedron
Make a deal with the Fellow Traveler for some relief from death's burden—and find out what it cost you
Finish the game on intended difficulty
Be late to the ending of your own story
Preserve monsters, wonders, and the plague, reviving the past
Face the future with Lara, Grief, and Stakh
Preserve the Town of humanity and warmth, giving it a future
Wait for the bull to speak
Watch every pantomime
Return to the Town once again
Tick-tock
Give names to all who are tongue-tied and mute
Bring something invaluable to the outside world
Be cured of sand plague by touching the Heart of the Town
Witness the arrival of Alexander Block
Find Grace's new home
Witness another Sky
"Why? What was the purpose of my life?"
Trade with children twenty-seven times
Witness the arrival of Aglaya Lilich
Wait with a friend for the next day to come
Test the new serum on yourself
Hear the Plague's voice
Lock up a shop to preserve a memory
Find a house suffering from an ailment other than sand pest
Save two children from infected houses
Come now, you haven't given us any time to change the set!
Find out if the immortal soul exists
See the Town's history on the walls
Return what you didn't deserve
Meet Measly and Thrush in a dream
Try your hand at train-summoning
Touch the thing that produces time
Hear the alarm bell tolling
Become cursed to remain silent… sometimes
Repay kindness in kind
Refuse fate—and face the consequences
Remind a colleague of the Hippocratic Oath—and fail
Feel the flow of time for the first time