Here is the full list of all 50 Pathologic 2 achievements. It takes around 0-1 hour to unlock all of the achievements on Windows.
Face the future with Lara, Grief, and Stakh
Witness all dreams—including those you'd rather not
Test the new serum on yourself
Lock up a shop to preserve a memory
Find out if the immortal soul exists
Be cured of sand plague by touching the Heart of the Town
Make a deal with the Fellow Traveler for some relief from death's burden—and find out what it cost you
Return to the Town once again
Jump from the Polyhedron
Give names to all who are tongue-tied and mute
Be late to the ending of your own story
Preserve monsters, wonders, and the plague, reviving the past
Finish the game on intended difficulty
Preserve the Town of humanity and warmth, giving it a future
Wait for the bull to speak
Disperse all Reflections
Watch every pantomime
Tick-tock
Bring something invaluable to the outside world
Witness the arrival of Alexander Block
Witness another Sky
Find Grace's new home
Witness the arrival of Aglaya Lilich
Wait with a friend for the next day to come
Hear the Plague's voice
Find a house suffering from an ailment other than sand pest
"Why? What was the purpose of my life?"
Save two children from infected houses
Return what you didn't deserve
Come now, you haven't given us any time to change the set!
Trade with children twenty-seven times
Hear the alarm bell tolling
See the Town's history on the walls
Touch the thing that produces time
Meet Measly and Thrush in a dream
Try your hand at train-summoning
Become cursed to remain silent… sometimes
Repay kindness in kind
Remind a colleague of the Hippocratic Oath—and fail
Refuse fate—and face the consequences
Feel the flow of time for the first time