Here is the full list of all 50 Pathologic 2 achievements. It takes around 0-1 hour to unlock all of the achievements on Windows.
Save two children from infected houses
Find out if the immortal soul exists
Come now, you haven't given us any time to change the set!
Refuse fate—and face the consequences
Remind a colleague of the Hippocratic Oath—and fail
Be cured of sand plague by touching the Heart of the Town
Be late to the ending of your own story
Preserve the Town of humanity and warmth, giving it a future
Finish the game on intended difficulty
Preserve monsters, wonders, and the plague, reviving the past
Wait for the bull to speak
Return to the Town once again
Tick-tock
Give names to all who are tongue-tied and mute
Bring something invaluable to the outside world
Witness the arrival of Alexander Block
Find Grace's new home
Jump from the Polyhedron
Witness another Sky
Test the new serum on yourself
Lock up a shop to preserve a memory
"Why? What was the purpose of my life?"
Try your hand at train-summoning
Repay kindness in kind
Touch the thing that produces time
Witness the arrival of Aglaya Lilich
Wait with a friend for the next day to come
Trade with children twenty-seven times
Find a house suffering from an ailment other than sand pest
See the Town's history on the walls
Hear the Plague's voice
Hear the alarm bell tolling
Return what you didn't deserve
Meet Measly and Thrush in a dream
Become cursed to remain silent… sometimes
Feel the flow of time for the first time
Witness all dreams—including those you'd rather not
Face the future with Lara, Grief, and Stakh
Disperse all Reflections
Make a deal with the Fellow Traveler for some relief from death's burden—and find out what it cost you
Watch every pantomime