Here is the full list of all 50 Pathologic 2 achievements. It takes around 0-1 hour to unlock all of the achievements on Windows.
Finish the game on intended difficulty
Preserve monsters, wonders, and the plague, reviving the past
Wait for the bull to speak
Return to the Town once again
Tick-tock
Give names to all who are tongue-tied and mute
Bring something invaluable to the outside world
Witness the arrival of Alexander Block
Witness another Sky
Touch the thing that produces time
Witness the arrival of Aglaya Lilich
Test the new serum on yourself
Hear the Plague's voice
Trade with children twenty-seven times
Hear the alarm bell tolling
See the Town's history on the walls
Return what you didn't deserve
Become cursed to remain silent… sometimes
Feel the flow of time for the first time
Come now, you haven't given us any time to change the set!
Repay kindness in kind
Remind a colleague of the Hippocratic Oath—and fail
Refuse fate—and face the consequences
Try your hand at train-summoning
Meet Measly and Thrush in a dream
Find a house suffering from an ailment other than sand pest
Witness all dreams—including those you'd rather not
Face the future with Lara, Grief, and Stakh
Disperse all Reflections
Jump from the Polyhedron
Find out if the immortal soul exists
"Why? What was the purpose of my life?"
Lock up a shop to preserve a memory
Wait with a friend for the next day to come
Save two children from infected houses
Preserve the Town of humanity and warmth, giving it a future
Be late to the ending of your own story
Make a deal with the Fellow Traveler for some relief from death's burden—and find out what it cost you
Find Grace's new home
Watch every pantomime
Be cured of sand plague by touching the Heart of the Town