Here is the full list of all 50 Pathologic 2 achievements. It takes around 0-1 hour to unlock all of the achievements on Windows.
Make a deal with the Fellow Traveler for some relief from death's burden—and find out what it cost you
Face the future with Lara, Grief, and Stakh
Return to the Town once again
Disperse all Reflections
Witness all dreams—including those you'd rather not
Give names to all who are tongue-tied and mute
Be cured of sand plague by touching the Heart of the Town
Find Grace's new home
Test the new serum on yourself
Wait with a friend for the next day to come
Find a house suffering from an ailment other than sand pest
Save two children from infected houses
Find out if the immortal soul exists
Return what you didn't deserve
Meet Measly and Thrush in a dream
Repay kindness in kind
Come now, you haven't given us any time to change the set!
Lock up a shop to preserve a memory
Try your hand at train-summoning
Jump from the Polyhedron
Remind a colleague of the Hippocratic Oath—and fail
Preserve monsters, wonders, and the plague, reviving the past
Preserve the Town of humanity and warmth, giving it a future
Finish the game on intended difficulty
Be late to the ending of your own story
Wait for the bull to speak
Watch every pantomime
Tick-tock
Bring something invaluable to the outside world
Witness the arrival of Alexander Block
Witness another Sky
Trade with children twenty-seven times
Witness the arrival of Aglaya Lilich
"Why? What was the purpose of my life?"
Hear the Plague's voice
See the Town's history on the walls
Hear the alarm bell tolling
Become cursed to remain silent… sometimes
Touch the thing that produces time
Refuse fate—and face the consequences
Feel the flow of time for the first time