Here is the full list of all 24 Nadir: A Grimdark Deckbuilder achievements.
Earn any Relics for the first time
Purchase any card in the shop
Earn any Filth for the first time
Defeat the Gunnery Demon
Defeat Beelzebub
Play the Saint's Blood card
Obtain any Rare card
Possess a Damned as a reward
Defeat Feaster from Afar
Defeat Fury
Defeat Lilith
Defeat Minos
Defeat Koschei the Immortal
Defeat Chernobog
Defeat King in Yellow
Unlock Vlad Tepes as a playable character
Unlock Hernan Cortes as a playable character
Defeat Belzebub
Defeat Moloch
Defeat Abaddon
Defeat Asmodeus
Earn any Skulls for the first time
Earn any Idols for the first time
Earn any Desires for the first time