Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat the boss in the first expedition
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Defeat Omega 6 times
Get 10 orange items in exchange for the trophies in camp
Get all the camp items
Die and resurrect 3 times in one expedition
Have 10 living skeletons in one battle
Defeat the Priestess 3 times
Defeat the hunter 3 times
Kill each enemy
Unlock all the encyclopedia
Craft 25 items
Synthesize 100 resources
Fill the whole map
Defeat Omega
See all the possible tiles
Build all the possible camp structures
Embark on your fiftieth expedition
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Build the river
Transmute 5 resources into hydrogen
Find all possible types of resources
Defeat the Hunter
Die outside of battle
Read 50 different dialogues
Unlock 50 chapters in the encyclopedia
Craft 5 items
Dismantle 10 items
Defeat the Priestess
Dismantle 5 items
Unlock a chapter in the encyclopedia
Defeat the Lich 3 times
Get 5 camp items
Complete 100 loops
Lose 100 resources
Die ten times
Unlock the ^Necromancer^ class
Drink 50 potions
Place 1000 cards
Find 100 resources
Defeat the Lich
Kill 1000 enemies
Unlock the ^Rogue^ class
Dismantle a camp structure
Embark on your tenth expedition
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition