Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Get all the camp items
Unlock all the encyclopedia
Die outside of battle
Defeat the hunter 3 times
Have 10 living skeletons in one battle
Kill each enemy
See all the possible tiles
Defeat the boss in the first expedition
Defeat Omega
Craft 25 items
Synthesize 100 resources
Build all the possible camp structures
Synthesize 5 resource with alchemy
Transmute 50 resources into hydrogen
Transmute 5 resources into hydrogen
Find all possible types of resources
Get 10 orange items in exchange for the trophies in camp
Build the river
Defeat the Priestess 3 times
Defeat the Hunter
Die and resurrect 3 times in one expedition
Dismantle a camp structure
Read 50 different dialogues
Defeat the Priestess
Dismantle 10 items
Unlock 50 chapters in the encyclopedia
Unlock a chapter in the encyclopedia
Fill the whole map
Dismantle 5 items
Craft 5 items
Embark on your fiftieth expedition
Get 5 camp items
Unlock the ^Necromancer^ class
Defeat the Lich 3 times
Unlock the ^Rogue^ class
Find 100 resources
Drink 50 potions
Complete 100 loops
Lose 100 resources
Place 1000 cards
Defeat the Lich
Kill 1000 enemies
Die ten times
Embark on your tenth expedition
Build the first camp structure
Die first time
Kill 5 enemies
Embark on your first expedition