Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Have 10 living skeletons in one battle
Unlock all the encyclopedia
Die outside of battle
Kill each enemy
Die and resurrect 3 times in one expedition
Defeat the Priestess 3 times
See all the possible tiles
Get all the camp items
Craft 25 items
Defeat the boss in the first expedition
Defeat Omega
Synthesize 100 resources
Embark on your fiftieth expedition
Defeat the hunter 3 times
Synthesize 5 resource with alchemy
Transmute 50 resources into hydrogen
Build all the possible camp structures
Transmute 5 resources into hydrogen
Build the river
Find all possible types of resources
Defeat the Hunter
Die ten times
Fill the whole map
Get 10 orange items in exchange for the trophies in camp
Read 50 different dialogues
Defeat the Priestess
Unlock 50 chapters in the encyclopedia
Dismantle 10 items
Dismantle a camp structure
Dismantle 5 items
Unlock a chapter in the encyclopedia
Lose 100 resources
Complete 100 loops
Drink 50 potions
Craft 5 items
Place 1000 cards
Get 5 camp items
Defeat the Lich 3 times
Unlock the ^Necromancer^ class
Kill 1000 enemies
Embark on your tenth expedition
Unlock the ^Rogue^ class
Find 100 resources
Defeat the Lich
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition