Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Defeat the boss in the first expedition
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Get 10 orange items in exchange for the trophies in camp
Kill each enemy
Unlock all the encyclopedia
See all the possible tiles
Have 10 living skeletons in one battle
Get all the camp items
Die outside of battle
Defeat Omega
Unlock 50 chapters in the encyclopedia
Unlock a chapter in the encyclopedia
Defeat the hunter 3 times
Synthesize 100 resources
Fill the whole map
Craft 25 items
Die and resurrect 3 times in one expedition
Dismantle a camp structure
Build all the possible camp structures
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Transmute 5 resources into hydrogen
Dismantle 10 items
Dismantle 5 items
Defeat the Hunter
Build the river
Defeat the Priestess 3 times
Read 50 different dialogues
Embark on your fiftieth expedition
Find all possible types of resources
Defeat the Priestess
Craft 5 items
Get 5 camp items
Unlock the ^Necromancer^ class
Defeat the Lich 3 times
Complete 100 loops
Die ten times
Unlock the ^Rogue^ class
Find 100 resources
Place 1000 cards
Defeat the Lich
Lose 100 resources
Drink 50 potions
Kill 1000 enemies
Embark on your first expedition
Kill 5 enemies
Build the first camp structure
Embark on your tenth expedition
Die first time