Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Unlock all the encyclopedia
Kill each enemy
Die and resurrect 3 times in one expedition
Get all the camp items
Have 10 living skeletons in one battle
Die outside of battle
Get 10 orange items in exchange for the trophies in camp
See all the possible tiles
Defeat Omega
Defeat the boss in the first expedition
Synthesize 100 resources
Defeat the hunter 3 times
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Build all the possible camp structures
Transmute 5 resources into hydrogen
Craft 25 items
Defeat the Hunter
Build the river
Defeat the Priestess 3 times
Find all possible types of resources
Embark on your fiftieth expedition
Defeat the Priestess
Unlock 50 chapters in the encyclopedia
Read 50 different dialogues
Dismantle a camp structure
Die ten times
Unlock a chapter in the encyclopedia
Fill the whole map
Defeat the Lich 3 times
Craft 5 items
Dismantle 10 items
Unlock the ^Necromancer^ class
Defeat the Lich
Get 5 camp items
Dismantle 5 items
Complete 100 loops
Lose 100 resources
Place 1000 cards
Find 100 resources
Drink 50 potions
Unlock the ^Rogue^ class
Embark on your tenth expedition
Kill 1000 enemies
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition