Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Defeat the hunter 3 times
Die ten times
Defeat the Priestess 3 times
Defeat the boss in the first expedition
Get 10 orange items in exchange for the trophies in camp
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Die and resurrect 3 times in one expedition
Defeat the Lich 3 times
Unlock all the encyclopedia
Kill each enemy
See all the possible tiles
Defeat Omega
Defeat the Hunter
Have 10 living skeletons in one battle
Fill the whole map
Transmute 50 resources into hydrogen
Get all the camp items
Craft 25 items
Build all the possible camp structures
Synthesize 100 resources
Synthesize 5 resource with alchemy
Transmute 5 resources into hydrogen
Read 50 different dialogues
Dismantle 10 items
Dismantle 5 items
Find all possible types of resources
Die outside of battle
Craft 5 items
Unlock 50 chapters in the encyclopedia
Build the river
Defeat the Priestess
Unlock a chapter in the encyclopedia
Dismantle a camp structure
Lose 100 resources
Embark on your fiftieth expedition
Defeat the Lich
Unlock the ^Necromancer^ class
Get 5 camp items
Complete 100 loops
Place 1000 cards
Drink 50 potions
Kill 1000 enemies
Find 100 resources
Embark on your tenth expedition
Unlock the ^Rogue^ class
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition