Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Defeat Omega 6 times
Defeat the boss in the first expedition
Have 10 living skeletons in one battle
Die outside of battle
Get 10 orange items in exchange for the trophies in camp
Unlock all the encyclopedia
Defeat Omega
Kill each enemy
Get all the camp items
Defeat the hunter 3 times
See all the possible tiles
Craft 25 items
Defeat the Hunter
Synthesize 100 resources
Fill the whole map
Find all possible types of resources
Build all the possible camp structures
Synthesize 5 resource with alchemy
Transmute 50 resources into hydrogen
Transmute 5 resources into hydrogen
Embark on your fiftieth expedition
Build the river
Defeat the Priestess 3 times
Die and resurrect 3 times in one expedition
Unlock 50 chapters in the encyclopedia
Unlock a chapter in the encyclopedia
Read 50 different dialogues
Dismantle a camp structure
Dismantle 10 items
Craft 5 items
Die ten times
Defeat the Lich 3 times
Dismantle 5 items
Complete 100 loops
Unlock the ^Rogue^ class
Lose 100 resources
Drink 50 potions
Defeat the Priestess
Place 1000 cards
Unlock the ^Necromancer^ class
Get 5 camp items
Embark on your tenth expedition
Find 100 resources
Defeat the Lich
Kill 1000 enemies
Embark on your first expedition
Die first time
Kill 5 enemies
Build the first camp structure