Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat the boss in the first expedition
Unlock all the encyclopedia
Defeat Omega 6 times
Kill each enemy
Defeat Omega
Have 10 living skeletons in one battle
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Get 10 orange items in exchange for the trophies in camp
Die outside of battle
See all the possible tiles
Die and resurrect 3 times in one expedition
Craft 25 items
Get all the camp items
Embark on your fiftieth expedition
Synthesize 100 resources
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Transmute 5 resources into hydrogen
Build all the possible camp structures
Defeat the Priestess 3 times
Find all possible types of resources
Unlock 50 chapters in the encyclopedia
Defeat the hunter 3 times
Defeat the Lich 3 times
Dismantle 10 items
Read 50 different dialogues
Build the river
Lose 100 resources
Fill the whole map
Defeat the Hunter
Unlock the ^Necromancer^ class
Die ten times
Complete 100 loops
Dismantle 5 items
Unlock a chapter in the encyclopedia
Defeat the Priestess
Get 5 camp items
Craft 5 items
Drink 50 potions
Place 1000 cards
Kill 1000 enemies
Defeat the Lich
Unlock the ^Rogue^ class
Find 100 resources
Embark on your tenth expedition
Dismantle a camp structure
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition