Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Get all the camp items
Get 10 orange items in exchange for the trophies in camp
Defeat the boss in the first expedition
Synthesize 100 resources
Transmute 50 resources into hydrogen
Unlock all the encyclopedia
Fill the whole map
Have 10 living skeletons in one battle
Kill each enemy
See all the possible tiles
Synthesize 5 resource with alchemy
Craft 25 items
Transmute 5 resources into hydrogen
Build all the possible camp structures
Defeat Omega
Defeat the Hunter
Unlock the ^Rogue^ class
Defeat the Priestess
Read 50 different dialogues
Dismantle a camp structure
Find all possible types of resources
Embark on your fiftieth expedition
Unlock a chapter in the encyclopedia
Unlock 50 chapters in the encyclopedia
Build the river
Dismantle 10 items
Dismantle 5 items
Unlock the ^Necromancer^ class
Get 5 camp items
Craft 5 items
Complete 100 loops
Die ten times
Place 1000 cards
Drink 50 potions
Lose 100 resources
Kill 1000 enemies
Find 100 resources
Embark on your tenth expedition
Defeat the Lich
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition
Die outside of battle
Defeat the Lich 3 times
Defeat the Priestess 3 times
Defeat the hunter 3 times
Defeat Omega 6 times
Die and resurrect 3 times in one expedition
Place 10 cards you didn't have in your deck, not counting ^Oblivion^