Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Drink 50 potions
Unlock the ^Rogue^ class
Place 1000 cards
Find 100 resources
Kill 1000 enemies
Embark on your tenth expedition
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition
Embark on your fiftieth expedition
Die ten times
Unlock the ^Necromancer^ class
Kill each enemy
Find all possible types of resources
Lose 100 resources
Dismantle a camp structure
Build the river
Build all the possible camp structures
Get 5 camp items
Get all the camp items
Craft 5 items
Craft 25 items
Dismantle 5 items
Dismantle 10 items
Synthesize 5 resource with alchemy
Synthesize 100 resources
Transmute 5 resources into hydrogen
Transmute 50 resources into hydrogen
Unlock a chapter in the encyclopedia
Unlock 50 chapters in the encyclopedia
Unlock all the encyclopedia
Read 50 different dialogues
Fill the whole map
See all the possible tiles
Die outside of battle
Complete 100 loops
Defeat the Lich
Defeat the Lich 3 times
Defeat the Priestess
Defeat the Priestess 3 times
Defeat the Hunter
Defeat the hunter 3 times
Defeat Omega
Defeat Omega 6 times
Die and resurrect 3 times in one expedition
Have 10 living skeletons in one battle
Get 10 orange items in exchange for the trophies in camp
Defeat the boss in the first expedition
Place 10 cards you didn't have in your deck, not counting ^Oblivion^