Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Defeat the boss in the first expedition
Have 10 living skeletons in one battle
Defeat Omega 6 times
Die outside of battle
Get 10 orange items in exchange for the trophies in camp
Unlock all the encyclopedia
Kill each enemy
See all the possible tiles
Get all the camp items
Defeat Omega
Die and resurrect 3 times in one expedition
Synthesize 100 resources
Fill the whole map
Defeat the hunter 3 times
Craft 25 items
Build all the possible camp structures
Dismantle 10 items
Dismantle 5 items
Unlock 50 chapters in the encyclopedia
Synthesize 5 resource with alchemy
Transmute 50 resources into hydrogen
Transmute 5 resources into hydrogen
Defeat the Hunter
Embark on your fiftieth expedition
Die ten times
Build the river
Unlock a chapter in the encyclopedia
Find all possible types of resources
Defeat the Priestess 3 times
Defeat the Lich 3 times
Read 50 different dialogues
Lose 100 resources
Craft 5 items
Dismantle a camp structure
Defeat the Priestess
Defeat the Lich
Drink 50 potions
Unlock the ^Necromancer^ class
Complete 100 loops
Get 5 camp items
Unlock the ^Rogue^ class
Place 1000 cards
Kill 1000 enemies
Find 100 resources
Embark on your tenth expedition
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition