Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Unlock all the encyclopedia
Have 10 living skeletons in one battle
Embark on your fiftieth expedition
Die outside of battle
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Get all the camp items
Synthesize 100 resources
Die and resurrect 3 times in one expedition
Craft 25 items
Defeat Omega
Kill each enemy
See all the possible tiles
Dismantle 10 items
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Transmute 5 resources into hydrogen
Build all the possible camp structures
Defeat the hunter 3 times
Defeat the Hunter
Dismantle a camp structure
Find all possible types of resources
Defeat the Priestess 3 times
Dismantle 5 items
Build the river
Get 10 orange items in exchange for the trophies in camp
Unlock 50 chapters in the encyclopedia
Unlock a chapter in the encyclopedia
Die ten times
Defeat the boss in the first expedition
Read 50 different dialogues
Defeat the Priestess
Lose 100 resources
Complete 100 loops
Unlock the ^Necromancer^ class
Craft 5 items
Get 5 camp items
Defeat the Lich 3 times
Drink 50 potions
Place 1000 cards
Embark on your tenth expedition
Unlock the ^Rogue^ class
Fill the whole map
Kill 1000 enemies
Find 100 resources
Defeat the Lich
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition