Here is the full list of all 50 Loop Hero achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Defeat Omega 6 times
Place 10 cards you didn't have in your deck, not counting ^Oblivion^
Die and resurrect 3 times in one expedition
Kill each enemy
Unlock all the encyclopedia
Defeat Omega
Have 10 living skeletons in one battle
Defeat the hunter 3 times
See all the possible tiles
Defeat the boss in the first expedition
Die outside of battle
Synthesize 100 resources
Get 10 orange items in exchange for the trophies in camp
Embark on your fiftieth expedition
Defeat the Priestess 3 times
Unlock a chapter in the encyclopedia
Unlock 50 chapters in the encyclopedia
Build all the possible camp structures
Build the river
Transmute 50 resources into hydrogen
Synthesize 5 resource with alchemy
Find all possible types of resources
Transmute 5 resources into hydrogen
Get all the camp items
Dismantle a camp structure
Defeat the Hunter
Read 50 different dialogues
Defeat the Priestess
Dismantle 10 items
Dismantle 5 items
Defeat the Lich 3 times
Unlock the ^Necromancer^ class
Craft 25 items
Craft 5 items
Get 5 camp items
Fill the whole map
Drink 50 potions
Defeat the Lich
Complete 100 loops
Die ten times
Place 1000 cards
Lose 100 resources
Find 100 resources
Kill 1000 enemies
Unlock the ^Rogue^ class
Embark on your tenth expedition
Die first time
Build the first camp structure
Kill 5 enemies
Embark on your first expedition