Here is the full list of all 50 Leap of Fate achievements.
Survive a One-Shot Kill card in which you lost health.
Unlock all of Rasimov's permanent upgrades.
Finish the game in Hard mode with Mukai.
Finish the game in Hard mode with Rasimov.
Finish the game in Normal mode with Rasimov.
Equip each of the 23 glyphs.
In a single playthrough, upgrade 6 skills from each of the three skill trees, and equip a gold glyph.
Complete 72 missions.
Finish the game in Normal mode with Big Mo.
Unlock all of Aeon's permanent upgrades.
Accept 30 combat modifiers.
Kill 7,500 creatures.
Survive the secret Cthulhu card in Hard mode
Finish the game in Normal mode with Aeon.
In a single combat, generate 60 reflected projectiles by shooting at a reflective-aura protected creature.
Finish the game with at least 7 keys, 7 energy cells and 1,500 mana.
Playing Mukai, finish the game by entering every card of every level (not counting extra cards or the shortcut card)
Finish the game in Normal mode with Mukai.
In a single playthrough, take no damage in a 3-skull combat card. Do this 10 times.
Clear every challenge type once.
Upgrade the same glyph twice in a single playthrough.
Equip a gold glyph.
Complete 20 missions.
Defeat 1,000 creatures with special kills.
Play with an alternate outfit.
Complete level 5.
Use a Continue.
Complete level 4.
Complete level 3.
Complete 5 missions.
Complete level 2.
Complete level 1.
Playing Aeon, finish the game by using Shadow Bolt to deal the killing blow on each of the guardians.
Playing Big Mo, finish the game without overheating once.
Playing Rasimov, activate the Immortal ability 6 times and finish the game with full health.
Unlock all of Big Mo's permanent upgrades.
Unlock all of Mukai's permanent upgrades.
Have 15 health.
Clear a level with special kills only.
In a single playthrough, reroll 3 shops, bypass 2 cards, and cast destiny runes once.
Kill 13 creatures with a single blow.
In level 4, be within the range of a doll head's swirl of minions for 20 seconds.
In a single playthrough, purchase 20 items in shops.
Finish the game without purchasing a single skill upgrade.
Finish the game without opening a single locked chest or locked card.
Finish the game without using any glyph.
Finish the game in Hard mode with Aeon.
Finish the game in Hard mode with Big Mo.
Complete 120 missions.
View every fate in the game.