Full list of all 51 Empire of Sin achievements.
The base game contains 46 achievements, and there is 1 DLC pack containing 5 achievements.
Win as Alphonse Capone
Kill Dean O'Banion
Kill Goldie Garneau
Kill Angelo Genna
Kill Sai Wing Mock
Kill Salazar Reyna
Kill Frank Ragen
Kill Elvira Duarte
Kill Joseph Saltis
Kill Maggie Dyer
Hire a gangster of each profession
Kill Stephanie St. Clair
Own five of each racket type
Kill Mabel Ryley
Land a hit with 10% or lower odds
Max the loyalty of one member of your crew
Kill Daniel McKee Jackson
Bribe a cop
Took over a neighborhood
Get a hotel and have all synergies simultaneously
Form a Business Arrangement
Perform an execution
Get a synergy bonus
Complete the tutorial
Kill Ronnie O'Neill
Take down all of an enemy's health with a single shot
Kill Frankie Donovan
Kill Alphonse Capone
Became Enemy of the State while maintaining the highest notoriety
Win as Dean O'Banion
Win as Maggie Dyer
Win as Frank Ragen
Win as Frankie Donovan
Win as Daniel McKee Jackson
Win as Joseph Saltis
Win as Elvira Duarte
Win as Mabel Ryley
Win as Goldie Garneau
Win as Sai Wing Mock
Win as Stephanie St. Clair
Win as Angelo Genna
Win as Salazar Reyna
Finish the game without recruiting a gangster
Finish the game without getting anyone in your crew killed
Collect all achievements
Have someone in your crew go to jail