Here is the full list of all 49 Deus Ex: Human Revolution achievements. It takes around 40-50 hours to unlock all of the achievements on Windows.
Perform 50 takedowns within the same playthrough. (Civilians don't count.)
It may take some sleuthing, but justice must be served.
You really nailed your case against Lee Hong.
Help the Hive Bartender settle a tab.
You paid poor Jaya's debt in full. How very... humane... of you.
Help a lady in the oldest of professions clean house.
You sent Diamond Chan on the trip of a lifetime.
You had an argument with your boss, David Sarif, and won.
You defeated Lawrence Barrett, elite member of a secret mercenary hit squad.
Put a grieving mother's doubts to rest.
Fully upgrade your first augmentation of choice.
Deal with the man in the shadows.
You made it through an entire hostile area without making so much as a squeak.
Successfully hack at least 50 devices within the same playthrough.
Deal with Mr. Carella's indiscretion.
You convinced Zeke Sanders to let his hostage go.
Upgrade your first weapon of choice.
Perform your first Hack successfully.
Perform your first Takedown. Civilians don't count, so be nice.
Knock out at least 100 enemies in a single playthrough.
Complete Deus Ex: Human Revolution.
Complete Deus Ex: Human Revolution at its hardest setting.
Experience all the different endings that Deus Ex: Human Revolution has to offer.
Complete Deus Ex: Human Revolution without anyone dying by your hand. (Boss fights do not count.)
Complete Deus Ex: Human Revolution without setting off any alarms.
Read all 29 unique XP books within a single playthrough.
Help Officer Nicholas take out the trash.
Follow Pritchard's lead to uncover the truth.
Protect a client's interests by performing a less-than-hostile takeover.
Descend into the bowels of an urban jungle and confront a warrior-priest.
Fully upgrade one of your weapons.
You defeated Yelena Federova, elite member of a secret mercenary hit squad.
You defeated Jaron Namir, Leader of Belltower's Elite Special Operations Unit.
You defeated Zhao Yun Ru and by doing so, destroyed the Hyron Project.
You found all the hidden story items in Megan's Office. Point-and-Click much?
You convinced Wayne Haas to let you into the morgue.
You convinced a fast-talking bartender to let you see Tong Si Hung.
You convinced the smooth-talking politician Bill Taggart to tell the truth in public.
You talked Doctor Isaias Sandoval out of suicide.
You pointed out the flaws in his logic to millionaire Hugh Darrow.
You watched the entire credit list and saw the surprise at the end.
Against all odds, you saved Faridah Malik's life.
You found and read the secret message. Now you know too much...
You kept Megan's bracelet for yourself. Apparently, letting go really is the hardest part.
Greedy bastard. You accepted O'Malley's blood money and let him go.
Maybe next time, Jacob will use a more complex code when arming a bomb.
You granted a dying man his final request.
You convinced Mengyao to spill the beans on the mysterious Hyron Project.
Seems you like playing with balls, eh?