Here is the full list of all 80 Astrea: Six-Sided Oracles achievements.
Reach max level with all Oracles.
Obtain all other achievements.
Reach max level with Orion.
Play at least 20 virtues in a single turn.
Win a battle with at least 20 Plague Hex die in your dice pool.
Defeat Astrea with all Oracles.
Defeat Astrea with Orion.
Win a Ground Zero battle without moving your Orbs.
Move your Orbs 50 times in a single battle.
Activate Astrium 4 times in a single turn.
Have at least 20 Soul Heat.
Reach max level with Sothis.
Have at least 4 creatures with at least 15 affliction.
Defeat Astrea with Sothis.
Have at least 30 Chanting.
Reach max level with Austra.
Score at least 7000 points in a run.
Defeat Corrupted Orion.
Defeat a boss on the first turn.
Win a run with only one type of dice other than Starter dice on your dice pool or with only Starter dice in your dice pool.
Win a run without any Epic die on your dice pool.
Deal 50 Purify with a Safe die.
Play a die with at least 50 Confuse on an Enemy without any Confuse percentage modifier.
Win a run with at least 15 Blessings.
Win a run without owning any Sentinels.
Defeat Astrea with Austra.
Dodge 4 Corruption in a row.
Defeat Corrupted Sothis.
Defeat Astrea with Hevelius.
Acquire 12 different type of Sentinels in a single run.
Reach max level with Hevelius.
Repair or Reactivate Sentinels at least 20 times in a single battle.
Have both your Sentinels with 4 types of Link.
Win a run with 10 or fewer dice on your dice pool.
Win a run with two Sentinels on max level.
Win a run without any Blessings.
Win a run without losing Hearts during battles. Sacrificing a Heart at Shrines doesn't count as Heart lost.
Win a run at Anomaly Level 8.
Reach max level with Cellarius.
Win a run with at least 50 dice on your dice pool.
Deal infinity Purify.
Reroll the same die at least 5 times in a single turn.
Defeat Astrea with Cellarius.
Defeat Corrupted Austra.
Prevent a Heart loss using Wave.
Reach max level with Moonie.
Win a run at Anomaly Level 3.
Defeat Astrea at Astrea Level 3.
Defeat Corrupted Hevelius.
Defeat the Corrupted version of yourself.
Defeat Corrupted Moonie.
Score at least 3500 points in a run.
Defeat Astrea with Moonie.
Defeat Astrea.
Defeat Astrea Avatar.
Defeat Corrupted Cellarius.
Enhance an enemy die.
Spend at least 1500 Star Shards in a single run.
Open Astrea's Heart.
Reach Astrea's Heart with Orion.
Make a creature receive at least 100 Purify in a single Purify instance.
Reach Astrea's Heart with Sothis.
Reach Astrea's Heart with Austra.
Reach Astrea's Heart with Hevelius.
Own a Sentinel on max level.
Reach Astrea's Heart with Cellarius.
Defeat Uncaged Anomaly.
Defeat Doomed Astronomer.
Defeat Sanctuary Parasite.
Score at least 2000 points in a run.
Reach Astrea's Heart with Moonie.
Defeat Decayed Star.
Play at least 10 dice in a single turn.
Defeat Corrupted Assembler.
Make an enemy defeat themselves.
Defeat Smoldering Beast.
Forge a die.
Acquire a Sentinel.
Win your first battle.
Save Meissa, the Antiquarian.