Here is the full list of all 30 Ascend: Hand of Kul achievements.
Slot 3 runes of any type into your armor or weapons
Defeat 3 player bosses
Spend 30,000 souls or purchase a Soul Pack
Ascend your first Caos
Kill 200 enemies
Perform 20 10-hit combos
Eat 20 Humans
Kill 25 enemies
Send a curse or blessing to another player
Create your first Caos and bind them to a god
Kill 1000 enemies
Get humans to kill 50 enemies for you
Kill 25 enemies with spells
Raise 3 shrines for your God
Curse 20 players
Bless 20 players
Banish 25 enemies into another player's realm
Cast 25 Crusade Spells
Have one of your Ascended Champions defeat another player
Purchase or discover a spell from each alignment
Transcended
Read all Highlands lore tomes
Defeat the Highlands Titan
Attained 200 points of physical damage
Attained 2000 points of armor
Looted 30 items or purchased 10 spells
Fully upgrade any spell
Use an Alignment Mask boost to access a restricted alignment dungeon
Reach player level 50 or Ascend 3 times
Contribute 50,000 points to the Crusade