Starts with any Cure Mode plague.
Use the "Field Research", "Censorship" and "Fake News" operations.
You have to wait for a pop-up to appear, this is random, so sometimes it will not appear, the pop-up will say a message about people believing that Field Research Operatives are placing mentally colored drugs in the water supply.
Note: After this pop-up appears, the infectivity of the disease will increase.