COLLECTABLE and
MISSABLEBefore leaving the subway station for the first time to Downtown Racoon City, you will find a clock to the left of the first typewriter in the game. On this clock, there is a dial in which you can insert 3 colored jewels (ruby, emerald and sapphire), which can be found within Fancy Boxes scattered through this part of the city.
Keep in mind that you need to insert the jewels before escaping through the subway. You'll notice you're at this point in the game after you restore the power (at the Power Station) and solve the Subway Office puzzle outlining the path for the subway. At this time, don't return to the Red Stone Street Station without getting all three jewels (or the Fancy Boxes) or the doors will close, and you will miss this trophy.
The location of the jewels is tied to the difficulty, their specific location is described below:
Assisted, Normal & HardcoreRuby: Inside the safe room at Moons Donuts.
Emerald: Inside the "Megaman" toy store. You need the lockpick to get into this store.
Sapphire: Right in front of the previous store, inside the mini market. You need the Bolt Cutters to get into this door.
You can also refer to the Additional Resources section for the location of all the Collectibles within the game in order of appearance, including some key items as the Fancy Boxes.
Nightmare / InfernoEmerald: At the back of the pharmacy, near the poster where you get the combination for the first safe.
Ruby: Inside the Subway Power Station, specifically where Drain Deimos resides, It is on top of a power box before climbing the stairs.
Sapphire: In a small alley in front of the back exit of Moon Donuts. You need the Bolt Cutters in order to gain access to this area.