Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
100% the game
Complete Sheol with Judas
Complete Sheol with Eve
Complete Sheol with Maggy
Complete Sheol with Isaac
Complete Sheol with Cain
Find Krampus in Satans room for a gift!
Make a Super Meat Boy!
Complete Sheol with ???
Complete the womb without taking damage
Complete the full game with ???
Complete the depths without taking damage
Complete the caves without taking damage
Complete the full game 10 times
Complete the full game 9 times
Complete the full game 8 times
Complete the full game 6 times
Complete the full game 7 times
You defeated Gish!
Complete the womb with Eve
Complete the full game 5 times
Give mom a taste of her own medicine!
Complete the full game with Maggy
Complete the full game 4 times
Complete the full game 3 times
Complete the full game with Judas
Complete the full game 2 times
Complete the full game with Cain
stay out of moms things!
ive lost my head one too many times...
Complete the full game
Collect 50+ pennies in one play through
Call death upon all of them!
i lost mine in the arcade...
Defeat all bosses in the depths
You defeated C.H.A.D.!
mom needs her pills! donate blood.
kill mom...
You defeated Steven!
Kids shouldnt play with matches...
Destroy the 7 Sins!
Dirty needles... eww
Defeat all bosses in the caves
Collect 7+ container hearts in one play through
Complete the basement without taking damage
Defeat all bosses in the basement
you dont wanna know where this bean has been...
Complete the Caves
i like to break things...
Make 2 deals with the devil in one play through
Kids shouldnt play with dead things...
Complete the basement
???
Complete Challenge 9
Complete Challenge 8
Complete Challenge 5
Complete the final chapter with Eve
Complete the final chapter with Samson
Complete Challenge 4
Complete Challenge 7
Complete the final chapter with ???
Complete the final chapter with Maggy
Complete the final chapter with Isaac
Complete the final chapter with Judas
Kill Satan with Samson
Complete Challenge 3
Kill moms heart with Samson
Complete Challenge 2
Complete Challenge 6
Complete Challenge 1
Complete the final chapter with Cain
Kill mom but pass on 2 treasure room items
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat Satan in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Isaac in Hardmode
Beat the game as Cain in Hardmode
Beat the game as Magdalen in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Eve in Hardmode
Beat the game as ??? in Hardmode, and good luck!
Beat the game as all characters in Hardmode.
100% the game and hardmode (get all the achievements)