Here is the full list of all 121 The Madness of Little Emma achievements.
Reach Undergrounds
Reach Den
Kill Haunt
Kill Green Viper
Kill a boss
Kill Liquid Sisters
Die
Reach Misery
Reach The Riddle
Unlock first ending
Unlock second ending
Unlock third ending
Unlock final ending
Find a secret
Kill all bosses in episode 1
Kill all bosses in episode 2
Kill all bosses in episode 3
Kill all bosses in episode 4
Kill 4 Seasons
Kill April
Find everything
Find a red chest
Complete ending 4 with clean mind all the time
Get really insane!
Collect 5 health bonuses in one game
Get very unlucky
Get very lucky
Unlock every other achievement
Complete episode 1 without collecting hearts and healing herbs
Complete episode 2 without collecting hearts and healing herbs
Complete episode 3 without collecting hearts and healing herbs
Complete episode 4 without collecting hearts and healing herbs
Destroy a turnip
Kill a shopkeeper
Buy 5 items in one playthrough
Have only 1 heart container
Kill Mask
Kill Alice
Kill the fat man
Kill Entozoon
Kill Red Viper
Kill Meat Bag
Kill Sinister Mask
Kill Manless Face
Kill Eidolon
Kill Spirit
Kill Summer
Kill Autumn
Kill Winter
Kill Spring
Find Love Burrow
Unlock Amelia
Unlock Elizabeth
Find all Love Items
Unlock fifth ending
Unlock sixth ending
Kill Manless Face as Amelia
Unlock Lucretia
Unlock Marah
Unlock Chloe
Complete Arena as Emma
Complete Arena
Complete Arena as Lucretia
Complete Arena as Elizabeth
Complete Arena as Amelia
Complete Arena as Marah
Complete Arena as Chloe