Here is the full list of all 25 The Enchanted Cave 2 achievements.
Complete the crafting section of the skill tree
Defeat the final boss
Completely fill one equipment section of the museum
Defeat the sorcerer
Reach character level 25
Defeat the Yeti
Craft 75 total potions
Save three people
Save two people
Complete the combat section of the skill tree
Equip an artifact in every equipment slot
Transmute an item
Discover 10 secret areas
Save one person
Craft 15 total potions
Successfully escape the cave with an artifact
Completely clear one floor of all enemies and loot
Completely fill all sections of the museum
Complete the magic section of the skill tree
Complete the Monster's Lair Challenge
Complete the Labyrinth Challenge
Complete Green Goo's Quest
Complete the main game in a single run
Complete a New Game +