Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Destroy a Strike Team in 15 seconds or less.
Fully upgrade Heller.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
10 or more kills with a single Black Hole attack.
Complete the game.
Complete the game on HARD difficulty.
Acquire all 46 upgrades through Consumes.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Destroy 5 helicopters using Pack Leader.
Destroy all Lairs.
20 or more kills with a single Hammerfist dive attack.
Destroy 5 vehicles using a Finisher.
10 or more kills using a single Bio-Bomb.
Mount a helicopter using Whipfist.
Reach the highest point in the world.
Complete LABOR OF LOVE.
Acquire 30 upgrades through Consumes.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Complete all //BLACKNET dossiers.
Simultaneously kill 2 Brawlers using a single Devastator.
Defeat all Field Ops teams.
Find all BlackBoxes.
Complete FALL FROM GRACE.
Weaponize 10 vehicles.
Consume 10 //BLACKNET targets.
Stealth hijack 5 tanks or APCs.
Acquire a Mutation in each of the 5 categories.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Counter enemy attacks 20 times using Shield.
Karate kick a helicopter.
Deflect 5 missiles at enemies using Shield Block.
Trigger 50 alerts.
Stealth Consume 50 Blackwatch troopers.
Complete a //BLACKNET operation.
5 consumes in 10 seconds or less.
Dismember a Brawler.
Acquire a Prototype Power.
Acquire 5 Mutations.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.