Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Complete all //BLACKNET dossiers.
Destroy 5 vehicles using a Finisher.
Complete the game.
Complete LABOR OF LOVE.
Mount a helicopter using Whipfist.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Acquire 30 upgrades through Consumes.
10 or more kills with a single Black Hole attack.
Simultaneously kill 2 Brawlers using a single Devastator.
Stealth Consume 50 Blackwatch troopers.
Complete FALL FROM GRACE.
Consume 10 //BLACKNET targets.
Acquire a Mutation in each of the 5 categories.
Destroy a single Lair.
Acquire 5 Mutations.
Counter enemy attacks 20 times using Shield.
Acquire 10 upgrades through Consumes.
Complete NATURAL SELECTION.
Trigger 50 alerts.
Deflect 5 missiles at enemies using Shield Block.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.
Find all BlackBoxes.
Defeat all Field Ops teams.
Destroy a Strike Team in 15 seconds or less.
5 consumes in 10 seconds or less.
Stealth hijack 5 tanks or APCs.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
20 or more kills with a single Hammerfist dive attack.
10 or more kills using a single Bio-Bomb.
Destroy 5 helicopters using Pack Leader.
Weaponize 10 vehicles.
Karate kick a helicopter.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Acquire all 46 upgrades through Consumes.
Reach the highest point in the world.
Destroy all Lairs.
Fully upgrade Heller.
Complete the game on HARD difficulty.