Here is the full list of all 43 Prototype 2 achievements. It takes around 20-25 hours to unlock all of the achievements on Windows.
Fully upgrade Heller.
Acquire all 46 upgrades through Consumes.
Complete the game on HARD difficulty.
Complete the game.
Complete LABOR OF LOVE.
Destroy 5 helicopters using Pack Leader.
Destroy a Strike Team in 15 seconds or less.
Karate kick a helicopter.
10 or more kills using a single Bio-Bomb.
Stealth hijack 5 tanks or APCs.
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Complete all //BLACKNET dossiers.
Mount a helicopter using Whipfist.
Find all BlackBoxes.
Destroy all Lairs.
10 or more kills with a single Black Hole attack.
Acquire 30 upgrades through Consumes.
Defeat all Field Ops teams.
Spend at least 25 consecutive seconds in the air (helicopters don't count).
Reach the highest point in the world.
Simultaneously kill 2 Brawlers using a single Devastator.
Destroy 5 vehicles using a Finisher.
Complete FALL FROM GRACE.
Consume 10 //BLACKNET targets.
Weaponize 10 vehicles.
20 or more kills with a single Hammerfist dive attack.
Acquire a Mutation in each of the 5 categories.
Destroy a single Lair.
Acquire 10 upgrades through Consumes.
Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Complete NATURAL SELECTION.
Counter enemy attacks 20 times using Shield.
Trigger 50 alerts.
Acquire 5 Mutations.
Stealth Consume 50 Blackwatch troopers.
Deflect 5 missiles at enemies using Shield Block.
5 consumes in 10 seconds or less.
Complete a //BLACKNET operation.
Dismember a Brawler.
Acquire a Prototype Power.
Meet Father Guerra.
Complete RESURRECTION.
Complete MEET YOUR MAKER.