Here is the full list of all 65 Defense Grid 2 achievements.
Sell 10 towers or more in a single mission.
Use the Precision Targeting Special Weapon (Rear Admiral Phillips).
Build 100 Laser towers.
Win a chapter 4 (or later) mission with level 3 towers only and no selling.
Use the command shuttle to move 6 map sections in Mission 6.
Enable a Tower Augmentation Item on 10 Towers.
Use the Tower Overcharge Special Weapon (Advisor Zacara).
Build 100 Inferno towers.
Build 100 Concussion towers.
Survive 100 waves on any Super Grinder challenge mode.
Survive 100 waves on Grinder challenge mode on any mission.
Using only Inferno towers, Win any chapter 4 (or later) mission.
Using only Cannon towers, Win any chapter 4 (or later) mission.
Build 100 Cannon towers.
Using only Gun towers, Win any chapter 4 (or later) mission.
Use the reload checkpoint option five times in a single mission.
Use the Temporal Cannon Special Weapon (Colonel Rissler).
Use the Resource Reinforcement Special Weapon (Professor Briel).
Use the Reload Checkpoint option.
Kill 10,000 aliens.
Using only level 1 towers, Win any Chapter 4 (or later) mission.
Complete the single player campaign in Story Mode.
Earn a silver medal (or better) on all missions in the Story mode.
Earn a gold medal on every mission in Story mode.
Win a Gold medal on mission 19 without using the Command Shuttle.
Build every tower and every upgrade for each tower.
Build and fully upgrade each tower type in one mission.
Beat a Chapter 4 mission or higher with zero cores captured.
Build 50 towers of any type in one mission.
Sell 10 towers.
Win a mission with at least 10,000 resources remaining.
Build 100 Gun towers.
Recover a loose core.
Kill an alien carrying a power core.
Save a core that is less than 10 seconds away from the map's exit point.
Build 1 of each tower type in any single mission.
Inspect 10 aliens.
Enable a Tower Augmentation item on any tower.
Kill 1000 aliens.
Finish all the missions in Chapter 1 in Story Mode.
Win a mission with at least 5,000 resources remaining.
Build 20 towers of any type in one mission.
Use the speed up control at 3x for a total of 60 seconds in any mission.
Earn a silver (or better) medal.
Earn a Gold Medal.
Kill an alien boss creature. (Juggernaut, Rumbler, Turtle, or Crasher)
Win a mission with at least 1,000 resources remaining.
Upgrade a level 1 tower to a level 2 tower.
Use the Orbital Laser Special Weapon (General Cai).
Win any mission without selling any towers.
Kill 100 aliens.
Kill 1 alien.
Earn Bronze on a Single Player mission.
Kill 50,000 aliens.
Build 100 Temporal towers.
Build 100 Meteor towers.
Build 100 Tesla towers.
Build 100 Missile towers.
Build 100 Boost towers.
Use the Core Teleport special weapon (Professor Taylor).
Earn 100 Gold Medals on any missions.
Play a Competitive Multiplayer mission.
Earn a Victory in a DG Fighter Multiplayer mission.
Earn Bronze in a Co-Op Multiplayer mission.
Earn Gold in a Co-Op Multiplayer mission.