Here is the full list of all 65 Defense Grid 2 achievements.
Earn 100 Gold Medals on any missions.
Kill 50,000 aliens.
Complete the single player campaign in Story Mode.
Earn a silver medal (or better) on all missions in the Story mode.
Earn a gold medal on every mission in Story mode.
Build 100 Temporal towers.
Use the Core Teleport special weapon (Professor Taylor).
Build 100 Tesla towers.
Build 100 Missile towers.
Win a Gold medal on mission 19 without using the Command Shuttle.
Use the command shuttle to move 6 map sections in Mission 6.
Build 100 Meteor towers.
Build 100 Concussion towers.
Using only level 1 towers, Win any Chapter 4 (or later) mission.
Build 100 Laser towers.
Survive 100 waves on any Super Grinder challenge mode.
Inspect 10 aliens.
Using only Inferno towers, Win any chapter 4 (or later) mission.
Survive 100 waves on Grinder challenge mode on any mission.
Beat a Chapter 4 mission or higher with zero cores captured.
Use the Precision Targeting Special Weapon (Rear Admiral Phillips).
Using only Cannon towers, Win any chapter 4 (or later) mission.
Using only Gun towers, Win any chapter 4 (or later) mission.
Win a chapter 4 (or later) mission with level 3 towers only and no selling.
Build 100 Gun towers.
Enable a Tower Augmentation Item on 10 Towers.
Kill 10,000 aliens.
Win a mission with at least 10,000 resources remaining.
Sell 10 towers or more in a single mission.
Use the Temporal Cannon Special Weapon (Colonel Rissler).
Build every tower and every upgrade for each tower.
Build 1 of each tower type in any single mission.
Build and fully upgrade each tower type in one mission.
Sell 10 towers.
Kill an alien boss creature. (Juggernaut, Rumbler, Turtle, or Crasher)
Build 50 towers of any type in one mission.
Finish all the missions in Chapter 1 in Story Mode.
Build 100 Inferno towers.
Build 100 Cannon towers.
Build 100 Boost towers.
Use the Resource Reinforcement Special Weapon (Professor Briel).
Use the Tower Overcharge Special Weapon (Advisor Zacara).
Earn a Victory in a DG Fighter Multiplayer mission.
Play a Competitive Multiplayer mission.
Earn Bronze in a Co-Op Multiplayer mission.
Earn Gold in a Co-Op Multiplayer mission.
Use the Orbital Laser Special Weapon (General Cai).
Enable a Tower Augmentation item on any tower.
Build 20 towers of any type in one mission.
Use the Reload Checkpoint option.
Use the reload checkpoint option five times in a single mission.
Kill 1000 aliens.
Win a mission with at least 5,000 resources remaining.
Recover a loose core.
Kill an alien carrying a power core.
Save a core that is less than 10 seconds away from the map's exit point.
Win any mission without selling any towers.
Use the speed up control at 3x for a total of 60 seconds in any mission.
Kill 100 aliens.
Kill 1 alien.
Earn a silver (or better) medal.
Earn a Gold Medal.
Win a mission with at least 1,000 resources remaining.
Upgrade a level 1 tower to a level 2 tower.
Earn Bronze on a Single Player mission.