Here is the full list of all 65 Defense Grid 2 achievements.
Using only Cannon towers, Win any chapter 4 (or later) mission.
Use the command shuttle to move 6 map sections in Mission 6.
Using only Gun towers, Win any chapter 4 (or later) mission.
Survive 100 waves on any Super Grinder challenge mode.
Survive 100 waves on Grinder challenge mode on any mission.
Using only Inferno towers, Win any chapter 4 (or later) mission.
Use the Core Teleport special weapon (Professor Taylor).
Complete the single player campaign in Story Mode.
Earn a silver medal (or better) on all missions in the Story mode.
Earn a gold medal on every mission in Story mode.
Kill 10,000 aliens.
Win a Gold medal on mission 19 without using the Command Shuttle.
Enable a Tower Augmentation Item on 10 Towers.
Win a chapter 4 (or later) mission with level 3 towers only and no selling.
Use the Precision Targeting Special Weapon (Rear Admiral Phillips).
Beat a Chapter 4 mission or higher with zero cores captured.
Win a mission with at least 10,000 resources remaining.
Build every tower and every upgrade for each tower.
Build and fully upgrade each tower type in one mission.
Build 1 of each tower type in any single mission.
Use the Temporal Cannon Special Weapon (Colonel Rissler).
Use the Tower Overcharge Special Weapon (Advisor Zacara).
Build 50 towers of any type in one mission.
Win a mission with at least 5,000 resources remaining.
Build 100 Boost towers.
Build 100 Gun towers.
Use the Resource Reinforcement Special Weapon (Professor Briel).
Enable a Tower Augmentation item on any tower.
Finish all the missions in Chapter 1 in Story Mode.
Win a mission with at least 1,000 resources remaining.
Sell 10 towers.
Kill 1000 aliens.
Build 20 towers of any type in one mission.
Recover a loose core.
Kill an alien carrying a power core.
Use the Reload Checkpoint option.
Use the reload checkpoint option five times in a single mission.
Use the Orbital Laser Special Weapon (General Cai).
Save a core that is less than 10 seconds away from the map's exit point.
Inspect 10 aliens.
Earn a silver (or better) medal.
Kill an alien boss creature. (Juggernaut, Rumbler, Turtle, or Crasher)
Upgrade a level 1 tower to a level 2 tower.
Win any mission without selling any towers.
Use the speed up control at 3x for a total of 60 seconds in any mission.
Earn a Gold Medal.
Earn Bronze on a Single Player mission.
Kill 100 aliens.
Kill 1 alien.
Kill 50,000 aliens.
Sell 10 towers or more in a single mission.
Build 100 Inferno towers.
Build 100 Laser towers.
Build 100 Temporal towers.
Build 100 Meteor towers.
Build 100 Tesla towers.
Build 100 Cannon towers.
Build 100 Missile towers.
Build 100 Concussion towers.
Using only level 1 towers, Win any Chapter 4 (or later) mission.
Earn 100 Gold Medals on any missions.
Play a Competitive Multiplayer mission.
Earn a Victory in a DG Fighter Multiplayer mission.
Earn Bronze in a Co-Op Multiplayer mission.
Earn Gold in a Co-Op Multiplayer mission.