Full list of all 20 SpaceChem achievements. It takes around 15-20 hours to unlock all of the achievements in the base game on Windows.
The base game contains 19 achievements, and there is 1 DLC pack containing 1 achievements.
Beat the assignment "No Ordinary Headache" using only one reactor.
Beat the assignment "Moustachium 608".
Beat the assignment "No Thanks Necessary" in under 2200 cycles.
Beat the assignment "Moustachium 604".
Beat the assignment "Moustachium 602".
Beat the assignment "Challenge: In-Place Swap".
Beat the assignment "Nothing Works" in under 1000 cycles.
Reach the south pole of Sernimir IV.
Beat the game!
Beat the assignment "Challenge: Going Green".
Beat the assignment "Challenge: Applied Fusion".
Beat the assignment "Challenge: KOHCTPYKTOP".
Beat the assignment "Gas Works Park" in under 2700 cycles.
Beat the assignment "Σ-Ethylene" in under 6000 cycles.
Beat the assignment "Falling" using two or fewer reactors.
Beat the assignment "Molecular Foundry" using two or fewer reactors.
Beat 3 published ResearchNet assignments.
Beat 10 published ResearchNet assignments.
Beat 20 published ResearchNet assignments.
Beat the assignment "Collapsar" in the 63 Corvi campaign.