Here is the full list of all 25 Big Pharma achievements.
Create and export a set of custom game settings.
Sell a product which Eases Migraine and Causes Headaches
Complete all the tutorial levels
Purchase every available plot on a 3x3 or larger map.
Use a Hadron Collider
Sell a product which Relieves Hypertension and Increases Blood Pressure.
Take out all three loans at the same time
Complete every challenge in the Beginner scenario.
Complete every challenge in the Intermediate scenario.
Complete every challenge in the Advanced scenario.
Complete every challenge in the Quick Start scenario.
Complete every challenge in the Crippling Debt scenario.
Complete every challenge in the Room to Maneuver scenario.
Complete every challenge in the Full Unlock scenario.
Complete 20 challenges with an Expert rating or higher.
Complete 20 challenges with a Master rating.
Sell a product which cures Alzheimer's Disease, Cures HIV and is a Cancer Vaccine.
Sell a product which contains four different active catalysts.
Sell a product which Combats Cancer and is Carginogenic
Sell a product which Reduces Anxiety and Encourages Anxiety.
Sell a product which Eases Asthma and Causes Breathing Difficulties.
Successfully analyse at least 20 different effects within a single game
Simultaneously sell one Pill, Cream, Syringe and Sachet.
Simultaneously own 5 active patents.
Include at least one random starting research and disabled research in a custom game.